| Charlie Hunnam | Jackson 'Jax' Teller |
| Katey Sagal | Gemma Teller Morrow |
| Mark Boone Junior | Robert 'Bobby Elvis' Munson |
| Dayton Callie | Wayne Unser |
| Kim Coates | Alexander 'Tig' Trager |
| Tommy Flanagan | Filip 'Chibs' Telford |
| Theo Rossi | Juan Carlos 'Juice' Ortiz |
| Maggie Siff | Dr. Tara Knowles Teller |
| Ron Perlman | Clarence 'Clay' Morrow |
| Rockmond Dunbar | Lieutenant Eli Roosevelt |
| Jimmy Smits | Nero Padilla |
| David Labrava | Happy Lowman |
| Chuck Zito | Frankie Diamonds |
| Peter Onorati | Leo Pirelli |
| McNally Sagal | Margaret Murphy |
| Chris Reed | Philip 'Filthy Phil' Russell |
| Jeff Wincott | James 'Jimmy' Cacuzza |
| Freddy Andreiuci | Petey |
| Karina Logue | Nurse Pam Toric |
| Rusty Coones | Rane Quinn |
| Bruno Amato | Hank |
| Gylberto Eusebio | Lucius Padilla |
| Evan Londo | Abel |
| Eileen Grubba | Precious Ryan |
| Ryder Londo | Abel |
| Vanessa Sheri | Crow Eater |
| Kurt Sutter | Otto |