| Charlie Hunnam | Jackson 'Jax' Teller |
| Katey Sagal | Gemma Teller Morrow |
| Mark Boone Junior | Robert 'Bobby Elvis' Munson |
| Kim Coates | Alexander 'Tig' Trager |
| Tommy Flanagan | Filip 'Chibs' Telford
(credit only) |
| Ryan Hurst | Harry 'Opie' Winston |
| Johnny Lewis | Kip 'Half Sack' Epps
(credit only) |
| William Lucking | Piermont 'Piney' Winston
(credit only) |
| Theo Rossi | Juan Carlos 'Juice' Ortiz |
| Maggie Siff | Dr. Tara Knowles |
| Ron Perlman | Clarence 'Clay' Morrow |
| Adam Arkin | Ethan Zobelle |
| Taylor Sheridan | Deputy Chief David Hale
(as Tayler Sheridan) |
| Dayton Callie | Chief Wayne Unser |
| Mitch Pileggi | Ernest Darby |
| Jamie McShane | Cameron Hayes |
| Callard Harris | Edmond Hayes |
| Sarah Jones | Polly Zobelle |
| Henry Rollins | AJ Weston |
| Kristen Renton | Ima Tite |
| Julie Ariola | Mary Winston |
| David Labrava | Happy |
| Marya Delver | Officer Eglee |
| Michael Patrick McGill | CSU Cop |
| Aaron Refvem | Cliff
(as Aaron Revfem) |
| Ruben Garfias | Sheriff
(as Rubèn Garfias) |
| Trenton Rogers | Duke |
| Aryn Nelson | Club Member
(uncredited) |