| Patrick Stewart | Capt. Jean-Luc Picard |
| Jonathan Frakes | Cmdr. William Riker |
| LeVar Burton | Lt. Cmdr. Geordi La Forge |
| Michael Dorn | Lt. Worf |
| Gates McFadden | Dr. Beverly Crusher |
| Marina Sirtis | Counselor Deanna Troi |
| Brent Spiner | Lt. Cmdr. Data |
| Colm Meaney | Chief Miles O'Brien |
| Pamela Winslow Kashani | Ensign McKnight
(as Pamela Winslow) |
| Rhonda Aldrich | Madeline |
| Whoopi Goldberg | Guinan |
| Patti Yasutake | Nurse Alyssa Ogawa |
| Tom Knickerbocker | Gunman
(as Thomas Knickerbocker) |
| Joyce Agu | Ensign Gates
(uncredited) |
| Majel Barrett | Enterprise Computer
(voice) (uncredited) |
| Michael Braveheart | Crewman Martinez
(uncredited) |
| Cameron | Ensign Kellogg
(uncredited) |
| Elliot Durant III | Starfleet Ensign
(uncredited) |
| Kathy Hammers | Ensign Locklin
(uncredited) |
| Randy James | Jones
(uncredited) |
| Lorine Mendell | Crewman Diana Giddings
(uncredited) |