| Taylor Schilling | Piper Chapman |
| Natasha Lyonne | Nicky Nichols |
| Uzo Aduba | Suzanne 'Crazy Eyes' Warren |
| Danielle Brooks | Tasha 'Taystee' Jefferson |
| Jackie Cruz | Marisol 'Flaca' Gonzales |
| Laura Gómez | Blanca Flores |
| Selenis Leyva | Gloria Mendoza |
| Taryn Manning | Tiffany 'Pennsatucky' Doggett |
| Adrienne C. Moore | Cindy Hayes |
| Matt Peters | Joel Luschek |
| Jessica Pimentel | Maria Ruiz |
| Dascha Polanco | Dayanara Diaz |
| Alysia Reiner | Natalie Figueroa |
| Elizabeth Rodriguez | Aleida Diaz |
| Nick Sandow | Joe Caputo |
| Dale Soules | Frieda Berlin |
| Yael Stone | Lorna Morello |
| Kate Mulgrew | Galina 'Red' Reznikov |
| Laura Prepon | Alex Vause |
| Catherine Curtin | Wanda Bell |
| Marcia DeBonis | Cathy |
| Daniella De Jesús | Zirconia Cabrera |
| Nick Dillenburg | CO Ryder Blake |
| Maria Dizzia | Polly Harper |
| Beth Dover | Linda Ferguson |
| Hunter Emery | CO Rick Hopper |
| Shannon Esper | Alana Dwight |
| Shawna Hamic | CO Virginia 'Ginger' Copeland |
| Susan Heyward | Tamika Ward |
| Mike Houston | CO Lee Dixon |
| Rebecca Knox | Tina Swope |
| Sipiwe Moyo | Adeola |
| Shirley Roeca | Juanita Vazquez |
| Finnerty Steeves | Beth Hoefler |
| Emily Tarver | CO Artesian McCullough |
| Christina Toth | Annalisa Damiva |
| Greg Vrotsos | CO Hellman |
| Nicholas Webber | CO Alvarez |
| Alicia Witt | Zelda |
| Lori Petty | Lolly Whitehill |
| Jason Biggs | Larry Bloom |
| Phumzile Sitole | Akers |
| Besanya Santiago | Creech |
| Tuli Roy-Kirwan | Swapna Majumdar |
| Marie-Lou Nahhas | Shani Abboud |
| Ismenia Mendes | Tali Grapes |
| Mandela Bellamy | Rosalie Deitland |
| Melinna Bobadilla | Santos Chaj |
| Dana Berger | Crystal Tawney |
| Ashleigh Sumner | Sylvia |
| Adam Lindo | Carlos 'Clitvack' Litvack |
| Major Attaway | Polycon Guard DeShaun McAdams |
| Jason Bowen | Quincy |
| Ruibo Qian | 'Mad Megan' Prince |
| Vin Knight | Dr. Wilhite |
| Jay Hieron | Man |
| Akeda Abrams | Nurse |
| Ellie Sanchez | Host |
| Shannon Beeby | Friend #1 |
| Conor McGee | Friend #2 |
| Jiho Kang | Waiter |
| Mindee Aviva | Inmate |
| Carla Carvalho | Ice Detainee |
| Courtney Gonzalez | D-Block Inmate |
| Claudette Lalí | Inmate |