| Taylor Schilling | Piper Chapman |
| Natasha Lyonne | Nicky Nichols |
| Uzo Aduba | Suzanne 'Crazy Eyes' Warren |
| Danielle Brooks | Tasha 'Taystee' Jefferson |
| Jackie Cruz | Marisol 'Flaca' Gonzales |
| Laura Gómez | Blanca Flores |
| Selenis Leyva | Gloria Mendoza |
| Taryn Manning | Tiffany 'Pennsatucky' Doggett |
| Adrienne C. Moore | Cindy Hayes |
| Matt Peters | Joel Luschek |
| Jessica Pimentel | Maria Ruiz |
| Dascha Polanco | Dayanara Diaz |
| Elizabeth Rodriguez | Aleida Diaz |
| Nick Sandow | Joe Caputo |
| Dale Soules | Frieda Berlin |
| Yael Stone | Lorna Morello |
| Kate Mulgrew | Galina 'Red' Reznikov |
| Laura Prepon | Alex Vause |
| Daniella De Jesús | Zirconia Cabrera |
| Nick Dillenburg | CO Ryder Blake |
| Beth Dover | Linda Ferguson |
| Hunter Emery | CO Rick Hopper |
| Shannon Esper | Alana Dwight |
| Amanda Fuller | Badison Murphy |
| Maggie Lacey | Prosecutor |
| Mackenzie Phillips | Barbara Denning |
| Alysia Reiner | Natalie Figueroa |
| Finnerty Steeves | Beth Hoefler |
| Christina Toth | Annalisa Damiva |
| Sipiwe Moyo | Adeola |
| Besanya Santiago | Creech |
| Shawna Hamic | CO Virginia 'Ginger' Copeland |
| Greg Vrotsos | CO Hellman |
| Vicci Martinez | Dominga 'Daddy' Duarte |
| Henny Russell | Carol Denning |
| Karina Ortiz | Margarita |
| Alexander Wraith | Vasily Reznikov |
| Mandela Bellamy | Rosalie Deitland |
| Phumzile Sitole | Akers |
| Reema Sampat | Shruti Chambal |
| Anita Keal | Elsie |
| Nedra Marie Taylor | Sylvia Guillen |
| Reji Woods | Orderly |
| Sharon Hope | Med Tech Sharon Chamberlain |
| Judy Wong | Silka Webb |
| Gina Jarrin | Doctor |
| Courtney Gonzalez | D-Block Inmate |