| Rami Malek | Elliot Alderson |
| Portia Doubleday | Angela Moss
(credit only) |
| Carly Chaikin | Darlene |
| Michael Cristofer | Phillip Price |
| Stephanie Corneliussen | Joanna Wellick
(credit only) |
| Martin Wallström | Tyrell Wellick |
| Grace Gummer | Dominique DiPierro
(credit only) |
| Christian Slater | Mr. Robot |
| Gloria Reuben | Krista Gordon |
| Michel Gill | Gideon Goddard |
| Azhar Khan | Mobley |
| Brian Stokes Mitchell | Scott Knowles |
| Joey Bada$$ | Leon |
| Sandrine Holt | Susan Jacobs |
| Erik Jensen | Frank Cody |
| Vaishnavi Sharma | Elliot's Mother |
| Aidan Liebman | Young Elliot |
| Bernadette Quigley | Chaplain |
| Tom Knutson | Creepy Man |
| Eve Lindley | Hot Carla |
| Anthony Jennings | Vincent |
| Sean Allan Krill | Kevin |
| Tim Miller | Doctor |
| Bonnie Black | Cheryl |
| Marisa Kennedy | Lily |
| Rebecca Kling | Loan Officer |
| Sebastian Chacon | Tad
(as Stephen Chacon) |
| Byrne Davis Jr. | Church Group Therapy
(uncredited) |
| Barack Obama | Self
(archive footage) (uncredited) |
| Leon Panetta | Self
(archive footage) (uncredited) |
| Lucy Teitler | Positive Affirmation Video Voice
(uncredited) |