| Charlie Cox | Matt Murdock |
| Deborah Ann Woll | Karen Page |
| Elden Henson | Foggy Nelson |
| Joanne Whalley | Sister Maggie |
| Jay Ali | Ray Nadeem |
| Wilson Bethel | Benjamin 'Dex' Poindexter |
| Stephen Rider | Blake Tower |
| Vincent D'Onofrio | Wilson Fisk |
| Geoffrey Cantor | Mitchell Ellison |
| Amy Rutberg | Marci Stahl |
| Danny Johnson | Benjamin Donovan |
| Stephen Rowe | Nicholas Lee |
| Kate Udall | SAC Tammy Hattley |
| Sunita Deshpande | Seema Nadeem |
| Max Baker | Dr. Myman |
| Holly Cinnamon | Julie Barnes |
| Meredith Salenger | Lily Ellison |
| Chris Carfizzi | Jason Ellison |
| Scotty Crowe | Agent Lim |
| Matthew McCurdy | Agent Wellers |
| Don Castro | Agent Arinori |
| Richard Prioleau | Agent Doyle |
| David Anthony Buglione | Agent Johnson |
| Josiah Nolan | Agent Mockta |
| Sam Slater | Agent O'Connor |
| Toni Di Buono | Arlene |
| Anna Reichert | Vexed Cop |
| Bruce Faulk | Installer |
| Dan Mason | Wealthy Guest |
| Josh Evans | Hotel Staffer |
| James Armato | Onlooker
(uncredited) |
| Frank Fernandez | Wealthy Hotel Patron
(uncredited) |
| JaQuinley Kerr | Business Owner
(uncredited) |
| Ashley North | Wealthy Hotel Patron
(uncredited) |
| And Palladino | Angry Protestor
(uncredited) |
| Ray Rosario | Wealthy Businessman
(uncredited) |
| Hank Strong | FBI Agent
(uncredited) |