| Jon Hamm | Don Draper |
| Elisabeth Moss | Peggy Olson |
| Vincent Kartheiser | Pete Campbell |
| January Jones | Betty Francis
(credit only) |
| Christina Hendricks | Joan Harris |
| Aaron Staton | Ken Cosgrove
(credit only) |
| Rich Sommer | Harry Crane |
| Kiernan Shipka | Sally Draper
(credit only) |
| Jessica Paré | Megan Draper |
| Kevin Rahm | Ted Chaough |
| Christopher Stanley | Henry Francis
(credit only) |
| Jay R. Ferguson | Stan Rizzo |
| Ben Feldman | Michael Ginsberg |
| Mason Vale Cotton | Bobby Draper
(credit only) |
| Robert Morse | Bertram Cooper |
| John Slattery | Roger Sterling |
| Linda Cardellini | Sylvia Rosen |
| James Wolk | Bob Benson |
| Michael Gaston | Burt Peterson |
| Christine Estabrook | Gail Holloway |
| Harry Hamlin | Jim Cutler |
| Trevor Einhorn | John Mathis |
| Craig Anton | Frank Gleason |
| Channing Chase | Dorothy 'Dot' Campbell |
| Rich Hutchman | Bud Campbell |
| Stephanie Drake | Meredith |
| Tracy Silver | Margie Koch |
| Kit Williamson | Ed |
| Christine Garver | Moira |
| Alexandra Ella | Clara |
| Richard Augustine | Bill |
| Cathy Lind Hayes | Nurse Finnegan |
| Craig Calman | SCDP Office Employee
(uncredited) |
| Timothy Douglas | SCDP Male
(uncredited) |
| Cary Huff | Sterling, Cooper Client
(uncredited) |
| Hudson Phillips | SCDP Male
(uncredited) |
| Devri Richmond | Secretary
(uncredited) |
| Lisa Y. Sheeler | SCDP Secretary
(uncredited) |