| Nicholas Asbury | DCI Woodgate |
| Robert Bannon | Andy King |
| Enzo Cilenti | Jeremy Lake |
| Dermot Crowley | DSU Martin Schenk |
| Idris Elba | DCI John Luther |
| Gary Hailes | Donnie McKinney |
| Sonita Henry | Daria Shubik |
| Anthony Howell | Palmer |
| Patrick Malahide | George Cornelius |
| Paul McGann | Mark North |
| Wunmi Mosaku | Detective Sgt. Catherine Halliday |
| Hermione Norris | Vivien Lake |
| Steven O'Neill | Simon Tipton |
| Andreea Paduraru | Ileana |
| Hiten Patel | PC Singh |
| Michael Smiley | Benny Silver |
| Matt Sproit | Cornelious Henchman |
| Glenn Webster | SCO19 Armed Police Officer |
| Ruth Wilson | Alice Morgan |
| Chris Cowlin | Police Officer
(uncredited) |
| Janette Sharpe | Police Officer
(uncredited) |