| Tom Ellis | Lucifer Morningstar |
| Lauren German | Chloe Decker |
| Kevin Alejandro | Dan Espinoza |
| D.B. Woodside | Amenadiel
(as DB Woodside) |
| Lesley-Ann Brandt | Mazikeen |
| Scarlett Estevez | Trixie Espinoza
(credit only) |
| Kevin Rankin | Malcolm Graham |
| Rachael Harris | Linda Martin
(credit only) |
| Heather Tom | Malcolm's Wife |
| Hal Ozsan | Sergei |
| Isiah Whitlock Jr. | Carmen |
| Lochlyn Munro | Anthony Paolucci |
| Anil Raman | Agent Pitts |
| Benjamin Arcé | Bouncer
(as Benjamin Arce) |
| Aiden Finn | Malcolm's Son |
| Ash Lee | Klause |
| Yaroslav Poverlo | Nikolas |
| Ashley Ross | Assistant |
| Patrick Sparling | Bodyguard |
| Ese Atawo | Bystander |
| Marlo Franson | Detective Marlo |
| Joy Osmanski | Alexandra Shaw |
| James Paladino | Hipster |
| Marisa Emma Smith | Tiffany |
| John Specogna | Detective Safari |
| Adil Zaidi | Grieving Man
(uncredited) |