| Dennis Farina | Detective Joe Fontana |
| Michael Imperioli | Detective Nick Falco |
| S. Epatha Merkerson | Lieutenant Anita Van Buren |
| Sam Waterston | E.A.D.A. Jack McCoy |
| Annie Parisse | A.D.A. Alexandra Borgia |
| Fred Thompson | D.A. Arthur Branch |
| Joseph Lyle Taylor | Davey Buckley |
| Peter McRobbie | Judge Walter Bradley |
| Matte Osian | James Buckley |
| J.D. Jackson | Lenny Thorne |
| Doc Dougherty | Sarge at Accident |
| Giancarlo Esposito | Rodney Fallon |
| Marsha Stephanie Blake | Clinic Doctor |
| John Randolph Jones | Engineer |
| John Boyd | Zach Burns |
| Leslie Elliard | Detective Jones |
| Henny Russell | Agent Melanie Moran |
| Guiesseppe Jones | Atkinson |
| Selenis Leyva | Detective Mariluz Rivera |
| Liz Larsen | CSU Technician Jessica Reed |
| Lizzy Davis | Assistant M.E. Carla Birch |
| Ron Scott | Tech |
| Wiley Wisdom | Jury Foreperson |
| Vince Cupone | Yankee Fan |
| David Shumbris | Boston Red Sox Fan |
| John Roney | Third Commuter |
| Ed Bogdanowicz | ESU Officer |
| Fast Ali | Commuter |
| Laura Lynn Berrios | Maureen Buckley |
| Robert Bizik | Crash Victim |
| Antonio Saillant | MTA Rescue Worker |
| Ilene Schwartz | Injured Commuter |
| Steven Zirnkilton | Narrator |