| Jerry Orbach | Detective Lennie Briscoe |
| Jesse L. Martin | Detective Ed Green |
| S. Epatha Merkerson | Lieutenant Anita Van Buren |
| Sam Waterston | E.A.D.A. Jack McCoy |
| Elisabeth Röhm | A.D.A. Serena Southerlyn |
| Dianne Wiest | Interim D.A. Nora Lewin |
| Dennis Boutsikaris | Defense Attorney Al Archer |
| Steven Rishard | Ray Burrows |
| Joan Copeland | Trial Judge Rebecca Stein |
| J.K. Simmons | Dr. Emil Skoda |
| Dominic Fumusa | Scott Turner |
| Kevin Henderson | Doug Larsen |
| Reuben Jackson | Dr. Paul Bernard |
| Andrea Navedo | Detective Ana Cordova |
| Gay Thomas Wilson | Andrea Reddick |
| Lisa Bostnar | Roberta Shields |
| Steve Blanchard | Pub Owner |
| Chuck Patterson | Lester Harkins |
| Leith Burke | Kenneth Underwood |
| Arnold Acevedo | Danny Moreno |
| Patti Chambers | Lauren Hughes |
| Danielle Flora | Amanda Marvin |
| Sarah Jenkins | Marley Shelton |
| Nancy Nutter | Foreperson |
| Tony Freeman | Irwin Henshall |
| Jennifer Riker | Waitress |
| Amro Salama | Cabbie |
| Phoebe Jonas | Emily |
| Curtis Mark Williams | Brad |
| John Pawlowski | Harold Shalowitz |
| Leith M. Burke | Kenneth Underwood |
| Daphna Cardinale | Clerk |
| Freddie Maas | Juror #12 |
| Steven Zirnkilton | Narrator |