| John Krasinski | Jack Ryan |
| Wendell Pierce | James Greer |
| Abbie Cornish | Cathy Mueller |
| Ali Suliman | Suleiman |
| Dina Shihabi | Hanin |
| John Hoogenakker | Matice |
| Timothy Hutton | Nathan Singer |
| Haaz Sleiman | Ali |
| Adam Bernett | Patrick Klinghoffer |
| Helmi Dridi | Omar Rahbini |
| Jameel Khoury | Colonel Al Radwan |
| Goran Kostic | Ansor Dudayev |
| Eileen Li | Noreen Yang |
| Emmanuelle Lussier Martinez | Teresa |
| Mena Massoud | Tarek Kassar |
| Victoria Sanchez | Layla Navarro |
| Victor Slezak | Joe Mueller |
| Nadia Affolter | Sara |
| Chadi Alhelou | Fathi |
| Kareem Tristan Alleyne | Army MP |
| Abanoub Andraous | Yemeni Plain Clothes Officer #1 |
| Arpy Ayvazian | Rama |
| Fayçal Azzouz | Yemeni PSO Officer #2 |
| Yanis Charifi | Young Ali |
| Kemaal Deen-Ellis | Pashtun Boy |
| Darren Harrity | Coast Guard Rescue Driver |
| Matthew Kabwe | CIA Security Guard |
| Charbel Makhlouf | Young Suleiman |
| Mohamed Marouazi | Yemeni PSO Captain |
| Tom Morehouse | Gordie Weld |
| Monique Pluard | Coast Guard Officer |
| Kenny Wong | Danny (Male Aide) |
| Karim Zein | Samir |
| Mehdi Aissaoui | Young Guard |
| Andreas Apergis | Pete Cortwright |
| Jonathan Bailey | Lance Miller |
| Joseph Balinas | Washington DC Elite |
| Tony Barber | Valet |
| Letitia Brookes | Vault Analyst #3 |
| Marie-Josée Croze | Sandrine |
| Olivia Dodson | Washington DC Elite |
| Brian Foreman | Washington DC Elite |
| Yolanda Henry | Washington Elite |
| Joost Janssen | Omega team |
| Kevin Kent | Omega Team |
| Seth Kozak | SPO #1 |
| Esther Lofgren | Rower |
| Todd C Sharbutt | Team Leader |
| Leo Staar | Williams |
| Jennifer Stokes | Washington Elite |
| Treava | Washington Elite |
| Alex Trebek | TV Host |
| Debbie Tsamoudakis | Washington DC Elite |
| Dan Verkman | Washington Elite |
| Marla Aaron Wapner | Waitress |