| Viola Davis | Annalise Keating |
| Billy Brown | Nate Lahey |
| Alfred Enoch | Wes Gibbins |
| Jack Falahee | Connor Walsh |
| Aja Naomi King | Michaela Pratt |
| Matt McGorry | Asher Millstone |
| Conrad Ricamora | Oliver Hampton |
| Karla Souza | Laurel Castillo |
| Charlie Weber | Frank Delfino |
| Liza Weil | Bonnie Winterbottom |
| Luna Lauren Velez | Soraya Hargrove
(as Luna Vélez) |
| Roxanne Hart | Sylvia Mahoney |
| Wilson Bethel | Charles Mahoney |
| Emily Swallow | Lisa Cameron |
| Suleka Mathew | Dana Benton |
| Corbin Reid | Meggy Travers |
| Mark L. Taylor | Vince Levin |
| Behzad Dabu | Simon Drake |
| Carlease Burke | A.D.A. Price |
| Matthew Risch | Thomas |
| Elena Campbell-Martinez | Judge Adrienne Whitman |
| Dawn Greenidge | Dr. Fenwick |
| Rico McClinton | Mark |
| Shiloh Nelson | Madison Cameron |
| Kurt Collins | Cashier |
| Lovlee Carroll | Reporter 1 |
| Thomas Daniel Smith | Reporter 2
(as Thomas Daniel) |
| David Caprita | Records Clerk |
| Ellana Barksdale | Court Staff |
| Tom Billett | Rough-Looking Guy |
| Nohely Quiroz | Law Student Lowell
(uncredited) |