| Viola Davis | Annalise Keating |
| Billy Brown | Nate Lahey |
| Alfred Enoch | Wes Gibbins |
| Jack Falahee | Connor Walsh |
| Aja Naomi King | Michaela Pratt |
| Matt McGorry | Asher Millstone |
| Karla Souza | Laurel Castillo |
| Charlie Weber | Frank Delfino |
| Liza Weil | Bonnie Winterbottom |
| Sarah Burns | Emily Sinclair |
| Conrad Ricamora | Oliver Hampton |
| Jefferson White | Philip Jessup |
| Judith Moreland | Virginia Wilder |
| Colby French | Barrett Nelson |
| Eric Lutes | Dale Madden |
| Susan Walters | Sharon Tidwell |
| Anna Belknap | Brenda |
| Famke Janssen | Eve Rothlo |
| Tom G. McMahon | Lloyd |
| Zoey Sidwell | Judge Lucy Modena |
| Jack Briggs | Prosser Lecht |
| Jae Jung | Woman |
| Carolyn Crotty | Philly Waitress |
| Valeska Grant | Asst to ADA Nelson
(uncredited) |
| Dani Haberman | Law Student
(uncredited) |
| Jarrell Hall | Customer
(uncredited) |
| Silawn Lewis | Courtroom Observer
(uncredited) |
| James Maple | Law Student
(uncredited) |
| Bruce M. Stockert | Man in Courtroom
(uncredited) |