| Viola Davis | Annalise Keating |
| Billy Brown | Nate Lahey |
| Alfred Enoch | Wes Gibbins |
| Jack Falahee | Connor Walsh |
| Katie Findlay | Rebecca Sutter |
| Aja Naomi King | Michaela Pratt |
| Matt McGorry | Asher Millstone |
| Karla Souza | Laurel Castillo |
| Charlie Weber | Frank Delfino |
| Liza Weil | Bonnie Winterbottom |
| Peter Onorati | Leo Lombardo |
| Michael McGrady | AUSA Hobbs |
| Karl Makinen | Paul Lombardo |
| April Parker Jones | Claire Bryce |
| Hector Luis Bustamante | Pedro Hortua
(as Hector Bustamante) |
| Marcia Gay Harden | Hannah Keating |
| Matthew Downs | Agent Anthony Fain |
| Thomas W. Ashworth | Mr. Fisher |
| Nelson Mashita | Judge Gene Escobar
(as Nelson Lee Mashita) |
| Jerry Hauck | Judge James Badgely |
| Cyrus Deboo | Professor Tim Dozier |
| Marie Caldare | Leo's Wife |
| Ellen Haun | Nervous Girl /
Ms. Chapin |
| Brandon Morales | Police Officer #1 |
| Bret Green | Police Officer #2 |
| Greg Collins | Police Officer #3 |
| Joy Benedict | Desk Reporter |
| Sara Welch | Field Reporter |
| Morgan Rae Egger | Law Student
(uncredited) |
| Jessyka Finnøy | Law Student
(uncredited) |
| Dani Haberman | Law Student
(uncredited) |
| Bruce M. Stockert | Reporter
(uncredited) |
| Tom Verica | Sam Keating
(archive footage) (uncredited) |