| Kevin Spacey | Francis Underwood |
| Robin Wright | Claire Underwood |
| Michael Kelly | Doug Stamper |
| Mahershala Ali | Remy Danton |
| Elizabeth Marvel | Heather Dunbar |
| Derek Cecil | Seth Grayson |
| Jimmi Simpson | Gavin Orsay |
| Nathan Darrow | Edward Meechum |
| Jayne Atkinson | Catherine Durant |
| Kim Dickens | Kate Baldwin |
| Paul Sparks | Thomas Yates |
| Christina Bennett Lind | Sharon |
| Jenna Stern | Eliana Caspi |
| John Harrington Bland | Congressman Carlson Greer |
| Carolyn Mignini | Congresswoman Rebecca Huntley |
| Bill Phillips | Reverend Jenkins |
| Chuck Todd | Chuck Todd |
| Bert Pence | Meet the Press Announcer |
| Ben Cunis | Maurice |
| Andy Clemence | Secretary of Labor |
| Nini Le Huynh | Claire's Assistant |
| Carol Anne Raffa | Claire's Secretary |
| Emilio Delgado | Ambassador Davila |
| Norman Brownstein | Diplomat |
| Rob Sheridan | Print Reporter |
| Danny Boushebel | Photographer |
| Patricia Prete | Stylist |
| Louis Murray | Taylor |
| Drepung Loseling Monks of the Mystical Arts of Tibet | Themselves |
| Dakota Romero | Woman Crossing Street |
| Liam Hughes | Older Man |
| Mary Suib | Older Woman |
| Peter Chiamardas | White House Press |
| Nakia Dillard | Soundman |
| Monica Haynes | 'Dunbar' Secret Service Agent |
| Neal McNeil | Wedding Photographer |
| Towanda Underdue | Secretary of Education |
| David Cohen | Dignitary |
| Rafael V. DeLeon | Party Goer |
| Kaelan Denali Dickinson | Cabinet Aide |
| Justin Doescher | Frank Underwood Security |
| Dawn A. Douglas | Claire Secret Service |
| Liam Ferguson | Press |
| Dave Ferrier | Videographer |
| Janet Devine Smith | Physical Therapist |
| Richard Strasser | Embassy Guest |
| Luke Van Bergen | Party Goer |
| John Wells | Diner Patron |