| Kevin Spacey | Francis Underwood |
| Robin Wright | Claire Underwood |
| Michael Kelly | Doug Stamper |
| Mahershala Ali | Remy Danton |
| Michel Gill | President Garrett Walker |
| Gerald McRaney | Raymond Tusk |
| Molly Parker | Jackie Sharp |
| Nathan Darrow | Edward Meechum |
| Jayne Atkinson | Catherine Durant |
| Jimmi Simpson | Gavin Orsay |
| Terry Chen | Xander Feng |
| Derek Cecil | Seth Grayson |
| Joanna Going | First Lady Tricia Walker |
| Rachel Brosnahan | Rachel Posner |
| Mozhan Marnò | Ayla Sayyad |
| Elizabeth Marvel | Heather Dunbar |
| Kate Lyn Sheil | Lisa Williams |
| Libby Woodbridge | Megan Hennessey |
| Benito Martinez | Hector Mendoza |
| Michael Park | Curtis Haas |
| Michael Warner | Oliver Spence |
| Jeremy Holm | Nathan Green |
| Mark Zeisler | Bill Galich |
| Tom Galantich | Thomas Larkin |
| Chris Hayes | Chris Hayes |
| Morris Jones | Morris Jones |
| Geoffrey Dawe | Tusk's Head Lawyer |
| Barney Fitzpatrick | Tusk's Lawyer #2 |
| Alex Webb | Agent Carter |
| Lance Lewman | Communication Director |
| Beth Hylton | Press Secretary |
| Michael Bonis | Dunbar's Associate |
| Altorro Prince Black | Secret Service Agent
(uncredited) |
| Tom Cutler | Tusk Lawyer
(uncredited) |
| Justin Doescher | Frank Underwood Security
(uncredited) |
| James Donahue | Walker Secret Service
(uncredited) |
| Mark Falvo | Photographer
(uncredited) |
| Debbie Hartner | Reporter
(uncredited) |
| Ken Holliday | Congressman at Press Conference
(uncredited) |
| Basil Kershner | Tusk's Driver
(uncredited) |
| James Mahony | Agent Phillips
(uncredited) |
| Jeremy McLain | Walker Secret Service
(uncredited) |
| Isabelle McNally | Kendra Lee
(uncredited) |
| Paola Torres | Concierge
(uncredited) |