| Kevin Spacey | Francis Underwood |
| Robin Wright | Claire Underwood |
| Michael Kelly | Doug Stamper |
| Mahershala Ali | Remy Danton |
| Michel Gill | President Garrett Walker |
| Gerald McRaney | Raymond Tusk |
| Molly Parker | Jackie Sharp |
| Nathan Darrow | Edward Meechum |
| Jayne Atkinson | Catherine Durant |
| Jimmi Simpson | Gavin Orsay |
| Derek Cecil | Seth Grayson |
| Rachel Brosnahan | Rachel Posner |
| Mozhan Marnò | Ayla Sayyad
(as Mozhan Marno) |
| Gil Birmingham | Daniel Lanagin |
| Elizabeth Norment | Nancy Kaufberger |
| Mark Zeisler | Bill Galich |
| Charles Borland | Captain Rockland |
| Sean Hannity | Sean Hannity |
| Rachel Maddow | Rachel Maddow |
| Chris Matthews | Chris Matthews |
| Julian Gamble | Chairman of Joint Chiefs |
| Ron Nakahara | Japanese Prime Minister |
| Timothy Crowe | Owner of Telegraph |
| Carver Hudson | Telegraph Legal Counsel |
| John Moon | Telegraph Executive Editor |
| Steven Gleich | Telegraph Managing Editor
(as Steve Gleich) |
| Celeste Jones | Telegraph Executive Assistant |
| Jefferson Farber | Bomber |
| Alonzo Bristol | Iowa Supporter
(uncredited) |
| Mike Cimatu | Secretary of Transportation
(uncredited) |
| Gregory Divers | Telegraph Reporter
(uncredited) |
| Justin Doescher | Frank Underwood Security
(uncredited) |
| James Donahue | Walker Secret Service
(uncredited) |
| Mark Falvo | Reporter
(uncredited) |
| Kristi Faye | First Underwood Staffer /
VP Receptionist
(uncredited) |
| Ken Holliday | Office Worker
(uncredited) |
| Basil Kershner | Tusk's Driver
(uncredited) |
| Kevin Laughon | Reporter
(uncredited) |
| Martin Lopez | Bartender
(uncredited) |
| Jody Matzer | White House Press
(uncredited) |
| Peter Muggleworth | Reporter
(uncredited) |
| Catalina Parks | Claire's Secret Service
(uncredited) |
| Robert Poletick | Defense Secretary Davis
(uncredited) |
| Jason Stolfi | Underwood Tactical Secret Service
(uncredited) |
| John Wells | Congressman
(uncredited) |
| Christopher Zash | Telegraph Mail Boy
(uncredited) |