| Kevin Spacey | Francis Underwood |
| Robin Wright | Claire Underwood |
| Michael Kelly | Doug Stamper |
| Sebastian Arcelus | Lucas Goodwin |
| Michel Gill | President Garrett Walker |
| Gerald McRaney | Raymond Tusk |
| Nathan Darrow | Edward Meechum |
| Jayne Atkinson | Catherine Durant |
| Terry Chen | Xander Feng |
| Jimmi Simpson | Gavin Orsay |
| Derek Cecil | Seth Grayson |
| Sam Page | Connor Ellis |
| Joanna Going | First Lady Tricia Walker |
| Mozhan Marnò | Ayla Sayyad
(as Mozham Marnò) |
| Jeremy Bobb | Nick Henslow |
| Jeremy Holm | Nathan Green |
| Deanna Dunagan | Susan Marbury |
| Margaret Daly | Elaine Brooks |
| Malcolm Madera | Augustus Underwood |
| Carolyn Michelle Smith | Willa |
| Joel Hurt Jones | Director |
| Ken Arnold | Vice Chief |
| Randall Newsome | Park Ranger |
| Matthew Foster | Manager |
| Grant Chang | Feng's Security Guard |
| Annie Chang | Feng's Assistant |
| Frances Eve | Young Woman at B&B |
| Jamie Nocher | Young Man at B&B |
| Jim Hild | Commissioner Roberts |
| Clinton Brandhagen | Photographer |
| Kevin Joel Anderson | Resort Guest
(uncredited) |
| Gary Ayash | Civil War Re-enactment Spectator
(uncredited) |
| Joanna Becker | Herald Staffer
(uncredited) |
| Adriaen Valéry Burgis | Investigative Journalist
(uncredited) |
| Paul H Chapman | Concierge
(uncredited) |
| Justin Doescher | Frank Underwood Security
(uncredited) |
| Lamont Easter | Underwood Secret Service
(uncredited) |
| Mark Falvo | Reporter
(uncredited) |
| Kristi Faye | First Underwood Staffer /
VP Receptionist
(uncredited) |
| Tom Gambrill | Newspaper Reporter
(uncredited) |
| Debbie Hartner | Guest at Confederate Field Dedication
(uncredited) |
| Kevin Hunt | Underwood Secret Service
(uncredited) |
| Ashley James | Underwood Assistant
(uncredited) |
| James Krehely | Re-enactment Visitor
(uncredited) |
| Joanna M. Lewis | Reporter
(uncredited) |
| Alex Martin | Union Soildier
(uncredited) |
| Jeremy McLain | Walker Secret Service
(uncredited) |
| Bert Puckett | Confederate Soldier
(uncredited) |
| J. Ryan Smith | Confederate Soldier
(uncredited) |
| Brian Stever | FBI Agent
(uncredited) |
| Dan Verkman | Civil War Reenactment Attendee
(uncredited) |