| Ben McKenzie | James Gordon |
| Donal Logue | Harvey Bullock |
| David Mazouz | Bruce Wayne |
| Zabryna Guevara | Sarah Essen |
| Sean Pertwee | Alfred Pennyworth |
| Robin Lord Taylor | Oswald Cobblepot /
Penguin |
| Erin Richards | Barbara Kean
(credit only) |
| Camren Bicondova | Selina Kyle |
| Cory Michael Smith | Edward Nygma |
| Victoria Cartagena | Renee Montoya
(credit only) |
| Andrew Stewart-Jones | Crispus Allen
(credit only) |
| John Doman | Carmine Falcone
(credit only) |
| Jada Pinkett Smith | Fish Mooney |
| Drew Powell | Butch Gilzean |
| Clare Foley | Ivy Pepper |
| Anthony Carrigan | Victor Zsasz |
| Niko Nicotera | Derek Delaware |
| Michael Eklund | Bob |
| Willie C. Carpenter | Leon Winkler |
| Berto Colon | Narco Cop #1
(as Berto Colón) |
| Carol Kane | Gertrude Kapelput |
| Dash Mihok | Detective Arnold Flass |
| Chelsea Spack | Kristen Kringle |
| J.W. Cortes | Detective Alvarez
(as JW Cortes) |
| Alex Corrado | Gabe |
| Phyllis Bash | Mrs. Winkler |
| Christine Hollingsworth | Zsasz Henchwoman #1 |
| Celia Au | Zsasz Henchwoman #2 |
| Lorrie Odom | Olga |
| Chris Santangelo | Carl |
| Fernando Mateo Jr. | Marco |
| Izzy Ruiz | Detective |
| Larry Nuñez | Anatoly |
| Diana Berry | GCPD Detective
(uncredited) |
| Adam Carbone | Gothamite
(uncredited) |
| Marmee Regine Cosico | Laundry Attendant
(uncredited) |
| Hans Marrero | Narco Cop #2
(uncredited) |
| Christopher Parker | Corrupt Cop
(uncredited) |
| Mirla Pereira | Police Officer
(uncredited) |
| Stuart Schnitzer | Core Desk Sergeant
(uncredited) |
| Nancy Wetzel | Zsasz Henchwoman #3
(uncredited) |