| James Gandolfini | Tony Soprano |
| Lorraine Bracco | Dr. Jennifer Melfi |
| Edie Falco | Carmela Soprano |
| Dominic Chianese | Junior Soprano |
| Steven Van Zandt | Silvio Dante |
| Tony Sirico | Paulie 'Walnuts' Gualtieri |
| Robert Iler | A.J. Soprano |
| Aida Turturro | Janice Soprano |
| Vincent Curatola | Johnny 'Sack' Sacramoni |
| Steve Schirripa | Bobby 'Bacala' Baccalieri |
| Joe Pantoliano | Ralph Cifaretto |
| Ray Abruzzo | Little Carmine Lupertazzi |
| Peter Bogdanovich | Dr. Elliot Kupferberg |
| Richard Portnow | Attorney Melvoin |
| Robert Funaro | Eugene Pontecorvo |
| Tony Lip | Carmine Lupertazzi |
| Paul Herman | Beansie Gaeta |
| Joseph R. Gannascoli | Vito Spatafore |
| Jessica Dunphy | Devin Pillsbury |
| Angelo Massagli | Bobby Baccalieri Jr. |
| Lexie Sperduto | Sophia Baccalieri |
| Alla Kliouka | Svetlana Kirilenka |
| Elena Solovey | Branca Libinsk |
| Tom Aldredge | Hugh DeAngelis |
| Suzanne Shepherd | Mary DeAngelis |
| Crystal Allen | Lisa |
| Joe Maruzzo | Joe Peeps |
| George Spaventa | V.I. Trifunovitch |
| Kevin Interdonato | Dogsy |
| Steve Santosusso | Anthony |
| Tony Darrow | Larry Barese |
| Randy N. Barbee | Judge Whitney R. Runions |
| Dan Castleman | Prosecutor |
| Joe Pucillo | Beppy Scerbo |
| Julie Ross | Court Clerk |
| Annabella Sciorra | Gloria Trillo |
| Patrick Ezerzer | Miami Mobster |
| Ethan S. Smith | Fountain Blue Bus Boy |