| James Gandolfini | Tony Soprano |
| Lorraine Bracco | Dr. Jennifer Melfi |
| Edie Falco | Carmela Soprano |
| Michael Imperioli | Christopher Moltisanti |
| Dominic Chianese | Junior Soprano |
| Steven Van Zandt | Silvio Dante |
| Tony Sirico | Paulie 'Walnuts' Gualtieri |
| Robert Iler | A.J. Soprano |
| Jamie-Lynn Sigler | Meadow Soprano |
| Drea de Matteo | Adriana La Cerva |
| Aida Turturro | Janice Soprano |
| Federico Castelluccio | Furio Giunta |
| John Ventimiglia | Artie Bucco |
| Steve Schirripa | Bobby 'Bacala' Baccalieri |
| Vincent Curatola | Johnny 'Sack' Sacramoni |
| Kathrine Narducci | Charmaine Bucco |
| Joe Pantoliano | Ralph Cifaretto |
| Jerry Adler | Hesh Rabkin |
| Peter Riegert | Assemblyman Zellman |
| Richard Romanus | Richard La Penna |
| Richard Portnow | Attorney Melvoin |
| Paul Schulze | Father Phil Intintola |
| Carl Capotorto | Little Paulie Germani |
| Robert Funaro | Eugene Pontecorvo |
| Joyce Van Patten | Dr. Sandy Shaw |
| Roma Maffia | Professor Longo-Murphy |
| Sharon Angela | Rosalie Aprile |
| Christine Pedi | Karen Baccalieri |
| Maureen Van Zandt | Gabriella Dante |
| Dan Grimaldi | Patsy Parisi |
| Joseph R. Gannascoli | Vito Spatafore |
| Max Casella | Benny Fazio |
| Montel Williams | Self |
| Joseph R. Sicari | Phillip Di Notti |
| Larry Sellers | Professor Del Redclay |
| Alex Rice | Maggie Donner |
| Frank Santorelli | Georgie |
| Tony Lip | Carmine Lupertazzi |
| Denise Borino-Quinn | Ginny Sack |
| Mary Aguilar | Cousin Grace |
| Jerry Grayson | Marty Schwartz |
| Yul Vazquez | Reuben 'the Cuban' |
| Val Bisoglio | Murf |
| Joe Pucillo | Beppy Scerbo |
| Nick Di Paolo | Joey the Cop |
| Robert Salas | Plain Tribesman |
| Irma-Estel LaGuerre | Native American Woman #1 |
| Sami Sargent | Native American Woman #2 |
| Tony Darrow | Larry Barese |
| Randy N. Barbee | Judge Whitney R. Runions |
| Dan Castleman | Prosecutor |
| Bruce MacVittie | Danny Scalercio |
| Julie Ross | Court Clerk |
| Angelo Massagli | Bobby Baccalieri Jr. |
| Lexie Sperduto | Sophia Baccalieri |
| Michael O'Looney | Newscaster |
| John Montone | Radio Reporter |
| Carmine Mitore | Zi'Pepin' |
| Donna Castellano | Cousin Mary |
| Nick Chinlund | Chief Doug Smith |
| Greg D'Agostino | Wiseguy |
| Kaye Kittrell | Sick Woman |
| Philip Ng | American Indian Protester |
| Craig Zucchero | Wiseguy |