| James Gandolfini | Tony Soprano |
| Lorraine Bracco | Dr. Jennifer Melfi |
| Edie Falco | Carmela Soprano |
| Michael Imperioli | Christopher Moltisanti |
| Dominic Chianese | Junior Soprano |
| Vincent Pastore | Salvatore 'Big Pussy' Bonpensiero |
| Steven Van Zandt | Silvio Dante |
| Tony Sirico | Paulie 'Walnuts' Gualtieri |
| Robert Iler | A.J. Soprano |
| Jamie-Lynn Sigler | Meadow Soprano |
| Drea de Matteo | Adriana La Cerva |
| David Proval | Richie Aprile |
| Aida Turturro | Janice Soprano |
| Saundra Santiago | Joan /
Jean Cusamano |
| Lillo Brancato | Matt Bevilaqua
(as Lillo Brancato Jr.) |
| Chris Tardio | Sean Gismonte |
| Federico Castelluccio | Furio Giunta |
| Paul Herman | Beansie Gaeta |
| Steve Schirripa | Bobby 'Bacala' Baccalieri
(as Steven R. Schirripa) |
| Joseph R. Gannascoli | Vito Spatafore
(as Joseph Gannascoli) |
| Vincent J. Orofino | Bryan Spatafore
(as Vinnie Orofino) |
| Tom Aldredge | Hugh DeAngelis |
| Susan Blackwell | Therapist |
| Joseph Carino | Secretary |
| Raymond Franza | Donny K |
| Patty McCormack | Liz La Cerva |
| Katalin Pota | Lilliana |
| Marek Przystup | Stasiu |
| Stelio Savante | Gaetano Giarizzo |
| Suzanne Shepherd | Mary DeAngelis
(as Suzanne Shepard) |
| Donna Smythe | Gia Gaeta |
| Vinny De Vingo | Badda Bing Patron
(uncredited) |
| John Doman | District Attorney
(uncredited) |