| James Gandolfini | Tony Soprano |
| Edie Falco | Carmela Soprano |
| Michael Imperioli | Christopher Moltisanti |
| Dominic Chianese | Junior Soprano |
| Vincent Pastore | Salvatore 'Big Pussy' Bonpensiero |
| Steven Van Zandt | Silvio Dante |
| Tony Sirico | Paulie 'Walnuts' Gualtieri |
| Jamie-Lynn Sigler | Meadow Soprano |
| Aida Turturro | Janice Soprano |
| Nancy Marchand | Livia Soprano |
| Sofia Milos | Annalisa |
| Louis Lombardi | Skip Lipari
(as Louis Lombardi Jr.) |
| Federico Castelluccio | Furio Giunta |
| Vittorio Duse | Zi Vittorio |
| Toni Kalem | Angie Bonpensiero |
| Mike Memphis | Jimmy Bones |
| Steve Schirripa | Bobby 'Bacala' Baccalieri
(as Steven R. Schirripa) |
| Sharon Angela | Rosalie Aprile |
| Jalil Jay Lynch | Partner
(as Jay Lynch) |
| Emme Shaw | Nurse |
| Maureen Van Zandt | Gabriella Dante |
| Ciro Maggio | Raffaelle |
| Danton Stone | Mr. Sontag |
| Melissa Weil | Mrs. Sontag |
| Jason Fuchs | Jr. Sontag |
| Jessica Peters | Sis Sontag |
| Gano Grills | Antonio |
| Anthony Alessandro | Waiter |
| Frankie Caero | Host
(as Frank Caero) |
| Pina Cutolo | Mother |
| Lello Giulivo | Camillo
(as Raffaele Giulivo) |
| Antonio Lubrano | Nino |
| Guido Palliggiano | Pino |
| Alida Tarallo | Prostitute |
| Alex Toma | Kid |
| Giuseppe Zeno | Tanno |
| Riccardo Zinna | Hotel Manager |
| David Chase | Italian Man
(uncredited) |