| Michael C. Hall | Dexter Morgan |
| Julie Benz | Rita Bennett |
| Jennifer Carpenter | Debra Morgan |
| C.S. Lee | Vince Masuka |
| Luna Lauren Velez | Lt. Maria LaGuerta
(as Lauren Velez) |
| David Zayas | Sgt. Angel Batista |
| James Remar | Harry Morgan |
| Jimmy Smits | ADA Miguel Prado |
| Desmond Harrington | Det. Joseph 'Joey' Quinn |
| David Ramsey | Anton Briggs |
| Valerie Cruz | Sylvia Prado |
| Kristin Dattilo | Det. Barbara Gianna |
| Jesse Borrego | George King |
| Jason Manuel Olazabal | Ramon Prado |
| Jane McLean | Tammy Okama |
| Frankie J. Allison | Det. Pratt
(as Frankie Jay Allison) |
| James Moses Black | Sgt. Jesse Whitaker |
| Christina Robinson | Astor Bennett |
| Preston Bailey | Cody Bennett |
| Paula Miranda | Sara Prado |
| Tasia Sherel | Francis |
| Sage Kirkpatrick | Laura Moser
(as Katherine Kirkpatrick) |
| Mary Alyce Kania | Karen |
| Victor Campos | Tailor |
| Jeremy Overstreet | Deputy |
| Sean Christopher Davis | Uniformed officer |
| Mark Bensi | Band Member: Drums
(uncredited) |
| Gary Calamar | Band Member
(uncredited) |
| Anna Hale | Cousin
(uncredited) |
| Bruce Holman | Det. Michael Soderquist
(uncredited) |
| Daniel Licht | Band Member: Keyboard
(uncredited) |
| Jon Licht | Band Member: Bass
(uncredited) |
| Pablo Soriano | Det. Robert Ramos
(uncredited) |
| Joseph Trapanese | Band Member: Trombone
(uncredited) |