| Michael C. Hall | Dexter Morgan |
| Julie Benz | Rita Bennett |
| Jennifer Carpenter | Debra Morgan |
| C.S. Lee | Vince Masuka |
| Luna Lauren Velez | Lt. Maria LaGuerta
(as Lauren Velez) |
| David Zayas | Sgt. Angel Batista |
| James Remar | Harry Morgan |
| Jimmy Smits | ADA Miguel Prado |
| Desmond Harrington | Det. Joseph 'Joey' Quinn |
| David Ramsey | Anton Briggs |
| Valerie Cruz | Sylvia Prado |
| Anne Ramsay | Ellen Wolf |
| Jason Manuel Olazabal | Ramon Prado |
| Jesse Borrego | George King |
| Christina Robinson | Astor Bennett |
| Preston Bailey | Cody Bennett |
| Jerry Zatarain Jr. | Mario Astorga |
| Jason Kaufman | Nathan Marten |
| Paula Miranda | Sara Prado |
| Louise Bennett | Court Files TV Reporter |
| Kristina Krofft | Yoga Instructor |
| Catalina Rodriguez | Woman Dancing |
| Aramis Knight | Carlos |
| Ray Santiago | Javier |
| Enzo Villaparedes | Singer |
| Bob Bencomo | Priest
(uncredited) |
| Melinda Bennett | Festival Salsa Dancer
(uncredited) |
| Brad Carr | College Dad
(uncredited) |
| Bruce Holman | Det. Michael Soderquist
(uncredited) |
| Silvia McClure | Doctor
(uncredited) |
| Karina Michel | Beth
(uncredited) |
| Christie Pesicka | Murder Victim
(uncredited) |
| Mary Scanlon | Dancer
(uncredited) |
| Pablo Soriano | Det. Robert Ramos
(uncredited) |
| Michael A. Templeton | District Attorney
(uncredited) |