| Anya Taylor-Joy | Beth Harmon |
| Bill Camp | Mr. Shaibel |
| Marielle Heller | Alma Wheatley |
| Isla Johnston | Young Beth Harmon |
| Patrick Kennedy | Allston Wheatley |
| Jacob Fortune-Lloyd | D.L. Townes
(archive footage) |
| Nikolai Jegorow | Russian Teacher |
| Sam Gilroy | Tim |
| Sophia Frank | Barbara |
| Salber Lee Williams | Eileen
(as Salber Williams) |
| Dolores Carbonari | Margaret
(archive footage) |
| Elvis Nowatzki | Margaret's Boyfriend
(archive footage) |
| Josepha Walter | Local Makeout Girl
(archive footage) |
| Marc Bergemann | Local Makeout Boy
(archive footage) |
| Rebecca Dyson-Smith | Stewardess |
| Pablo Scola | Manuel |
| Matthew Dennis Lewis | Matt |
| Russell Dennis Lewis | Mike |
| Rahul Chakraborty | Vendor |
| Paul Walther | Vendor #2 |
| Marcin Dorocinski | Vasily Borgov |
| Janina Elkin | Borgov's Wife |
| Matteo Vinogradov | Borgov's Child |
| Felice | Marceno
(as Carlo Felice Audrines) |
| Alberto Ruano | Director |
| Jan Nahuel Häfliger | Alberto Diaz
(as Nahuel Häfliger) |
| Adrian Zwicker | Diedrich |
| Louis Ashbourne Serkis | Girev |
| Andruscha Hilscher | Russian
(voice) |
| Iskander Madjitov | Another Russian |
| Tatsu Carvalho | Doctor |
| Andreas Muñoz | Manager |
| Ivan Gallardo | Farmacia Man
(as Iván Gallardo-Baez) |