| Jason Bateman | Michael Bluth |
| Portia de Rossi | Lindsay Bluth Fünke |
| Will Arnett | Gob Bluth |
| Michael Cera | George-Michael Bluth |
| Alia Shawkat | Maeby Fünke |
| Tony Hale | Buster Bluth |
| David Cross | Tobias Fünke |
| Jeffrey Tambor | George Bluth Sr. /
Oscar Bluth |
| Jessica Walter | Lucille Bluth |
| James Lipton | Warden Stefan Gentles |
| Kenneth Kimmins | Doctor Carr
(as Ken Kimmins) |
| Hector Atreyu Ruiz | Sheriff |
| Cameron Covell | Boy Prisoner #1 |
| Andrew Vo | Boy Prisoner #2 |
| Ruby Jossen | Girl Lucille |
| Mackenzie Hannigan | Boy Gentles |
| Sema'Jay Hall | African-American Boy Inmate |
| Rosemary Garris | Charity Guest
(uncredited) |
| Toby Holguin | Prisoner #1
(uncredited) |
| Ron Howard | Narrator
(voice) (uncredited) |
| Brea Tisdale | Woman
(uncredited) |
| Dan Warner | Prison Guard
(uncredited) |